Linear decline in serum alkaline phosphatase activity during treatment of renal osteodystrophy.
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چکیده
منابع مشابه
New Biochemical Serum Markers of Bone Turnover in Renal Osteodystrophy
Renal osteodystrophy is a multifactorial disorder of bone remodelling that develops in patients with chronic renal failure. During the last few years numerous biochemical markers of bone turnover have been proposed for the non-invasive diagnosis of renal osteodystrophy. Several enzymes and matrix proteins produced by osteoblasts and osteoclasts, including collagen type I degradation products, h...
متن کامل1 alpha-hydroxy vitamin D3 treatment of non-dialyzed patients with chronic renal failure. Effects on bone, mineral metabolism and kidney function.
Nine non-dialyzed patients with creatinine clearance below 20 ml/min and histological and biochemical signs of renal osteodystrophy received 1 alpha-hydroxy vitamin D3 for 6 months in a mean daily dosage of 0.9 microgram. The serum concentrations of calcium and phosphate increased, and the serum concentrations of alkaline phosphatase and parathyroid hormone decreased during treatment. Quantitat...
متن کاملA case of renal osteodystrophy with unexpected serum intact parathyroid hormone concentrations.
A 64-year-old female with long-standing end-stage renal disease (ESRD), status post 2 failed renal transplants, was evaluated for management of renal osteodystrophy with particular concern for adynamic bone disease (ABD). ABD was suspected because of low normal serum intact parathyroid hormone (PTH) concentrations (range 2.5–54 ng/L, reference range 10–65 ng/L), intermittently increased serum c...
متن کاملBone alkaline phosphatase isoenzyme in renal osteodystrophy.
Serum total alkaline phosphatase is the most commonly used biochemical marker of bone disease in renal patients, but alkaline phosphatase originates from different organs and sometimes lacks specificity. Bone isoenzyme measurement is considered superior to total alkaline phosphatase for the assessment of bone metabolism. We have studied the value of bone isoenzyme, determined by a new. IRMA (Ta...
متن کاملModerate strontium loading induces rickets in rats with mild chronic renal failure.
BACKGROUND/AIMS Renal osteodystrophy and eventually osteoporosis are serious long-term complications in children with end-stage renal disease before and after renal transplantation. Strontium (Sr) salts are used for treatment of osteoporosis in adults. METHODS To evaluate the time-dependent effects of Sr on growth plate morphology and their reversibility, chronic renal failure (CRF) rats rece...
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ورودعنوان ژورنال:
- British medical journal
دوره 286 6359 شماره
صفحات -
تاریخ انتشار 1983